Development of huperzine A and B for treatment of Alzheimer's disease

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Development of huperzine A and B for treatment of Alzheimer's disease

Recent studies have proved that huperzine A (HupA) possesses different pharmacological actions other than the inhibition of hydrolysis of ACh. These noncholinergic roles, for instance, the antagonist effect on NMDA receptor, the protection of neuronal cells against β-amyloid, free radicals, and hypoxia-ischemia-induced injury, could be important too in Alzheimer’s disease (AD) treatment. The th...

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ژورنال

عنوان ژورنال: Pure and Applied Chemistry

سال: 2007

ISSN: 1365-3075,0033-4545

DOI: 10.1351/pac200779040469